منابع مشابه
Salmeterol in paediatric asthma.
BACKGROUND The addition of long acting inhaled beta(2) agonists is recommended at step 3 of the British guidelines on asthma management but a recent study suggested no additional benefit in children with asthma. METHODS The aim of this study was to compare, in a double blind, three way, crossover study, the effects of the addition of salmeterol 50 microg bd, salmeterol 100 microg bd, and salb...
متن کاملThe effect of salmeterol on nocturnal symptoms, airway function, and inflammation in asthma.
STUDY OBJECTIVE To determine the efficacy of salmeterol alone in a group of patients with moderate asthma with nocturnal worsening of symptoms. DESIGN Double-blind, randomized, placebo-controlled crossover study. SETTING Tertiary care hospital specializing in respiratory diseases. PARTICIPANTS Ten patients with nocturnal asthma. INTERVENTIONS Subjects were randomized to salmeterol, 100 ...
متن کاملSalmeterol vs theophylline: sleep and efficacy outcomes in patients with nocturnal asthma.
STUDY OBJECTIVES To compare the efficacy, safety, and effects on sleep quality of salmeterol and extended-release theophylline in patients with nocturnal asthma. DESIGN Randomized, double-blind, double-dummy, three-period crossover. SETTING Outpatients at a single center. Patients spent 1 night during screening and 2 nights during each study period in a sleep laboratory for completion of sl...
متن کاملNocturnal cough in asthma.
The timing of nocturnal cough and its association with change in ambient temperature was documented in 11 asthmatic children, median age 5.1 years, while they were receiving continuous prophylaxis. Studies were performed in their homes on three nights. A voice activated system with electronic time signal recorded coughing. Ambient temperature was recorded every five minutes throughout the night...
متن کاملSodium cromoglycate in nocturnal asthma.
To investigate whether mast cell degranulation was important in producing nocturnal asthma, the effect of a single high dose of nebulised sodium cromoglycate on overnight bronchoconstriction, oxygen saturation, and breathing patterns in eight patients with nocturnal wheeze was examined. The study took the form of a double blind placebo controlled crossover comparison. Treatment with cromoglycat...
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ژورنال
عنوان ژورنال: BMJ
سال: 1991
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.302.6772.347-a